Hodgkin-Huxley Equations
Next, the conductance of Sodium and Potassium is calculated using the
following equations:
gNa = (120(m3)h)
gK = (36(n4))
where m, n and h are values that represent the gates that provide access
through the Sodium and Potassium
channels. (Refer to
Biological Background for more details on these channels) The following equations are used to determine the values for m, n
and h.
dm/dt =
alpham(Vm(1-m)-(Betam(Vm)(m))
dn/dt =
alphan(Vm(1-n)-(Betan(Vm)(n))
dh/dt = alphah(Vm(1-h)-(Betah(Vm)(h))
where
alpham = (.1(Vm+25)/(exp((Vm+25)/10)-1)
alphan = (.01(V+10)/exp((Vm+10)/10)-1)
alphah = (.07(exp(Vm/20)
Betam = 4exp(Vm/18)
Betan = ((1/(exp((Vm+30)/10)+1)
Betah = .125exp(Vm/80)
and m, n and h are initial values calculated using the resting membrane
potential
After obtaining conductance, the membrane current can be calculated using the
following equation
I =
(((gNa(m3)(h)(Vm-VNa)+(gK
(n4)(Vm-VK)
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